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COG classification of genes. (A) Clusters of orthologous genes (COGs) distribution among the 52 M. <t>hominis</t> strains associated with infertility. (B) COGs distribution among the 10 M. hominis strains associated with genital infections. Bars in green, red, and blue, represent the core genome, the accessory genes (shell genes), and unique genes (cloud genes), respectively.
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Co-infection numbers of several Mycoplasma spp. UU = Ureaplasma urealyticum ; UP = Ureaplasma parvum ; MH = <t>Mycoplasma</t> <t>hominis</t> ; MG = Mycoplasma genitalium ; MF = Mycoplasma fermentans .
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COG classification of genes. (A) Clusters of orthologous genes (COGs) distribution among the 52 M. hominis strains associated with infertility. (B) COGs distribution among the 10 M. hominis strains associated with genital infections. Bars in green, red, and blue, represent the core genome, the accessory genes (shell genes), and unique genes (cloud genes), respectively.

Journal: Frontiers in Microbiology

Article Title: A genome-wide investigation of Mycoplasma hominis genes associated with gynecological infections or infertility

doi: 10.3389/fmicb.2025.1561378

Figure Lengend Snippet: COG classification of genes. (A) Clusters of orthologous genes (COGs) distribution among the 52 M. hominis strains associated with infertility. (B) COGs distribution among the 10 M. hominis strains associated with genital infections. Bars in green, red, and blue, represent the core genome, the accessory genes (shell genes), and unique genes (cloud genes), respectively.

Article Snippet: The genome size of M. hominis reference strain PG21 (ATCC 23114) was estimated to be around 665 kb (Calcutt and Foecking, ), thus exceeding Mycoplasma genitalium genome (580 kb), the smallest genome of any organism that can be grown in pure culture (Fookes et al., ), by only 85 kb.

Techniques:

Single nucleotide polymorphism (SNP) distribution among M. hominis strains associated with gynecological infections (red boxplot) and infertility (blue boxplot). Student's t -test was used to assess for statistical significant difference ( P < 0.05) between the mean SNPs count values of strains linked to infertility and gynecological infections. * Represents the mean SNP count of each boxplot.

Journal: Frontiers in Microbiology

Article Title: A genome-wide investigation of Mycoplasma hominis genes associated with gynecological infections or infertility

doi: 10.3389/fmicb.2025.1561378

Figure Lengend Snippet: Single nucleotide polymorphism (SNP) distribution among M. hominis strains associated with gynecological infections (red boxplot) and infertility (blue boxplot). Student's t -test was used to assess for statistical significant difference ( P < 0.05) between the mean SNPs count values of strains linked to infertility and gynecological infections. * Represents the mean SNP count of each boxplot.

Article Snippet: The genome size of M. hominis reference strain PG21 (ATCC 23114) was estimated to be around 665 kb (Calcutt and Foecking, ), thus exceeding Mycoplasma genitalium genome (580 kb), the smallest genome of any organism that can be grown in pure culture (Fookes et al., ), by only 85 kb.

Techniques:

TreeWAS-based phylogenetic tree illustrating the relatedness between the 62 Tunisian M. hominis clinical strains based on pathotype association. Strains in red are associated with gynecological infections pathotype and strains in blue are associated with infertility pathotype.

Journal: Frontiers in Microbiology

Article Title: A genome-wide investigation of Mycoplasma hominis genes associated with gynecological infections or infertility

doi: 10.3389/fmicb.2025.1561378

Figure Lengend Snippet: TreeWAS-based phylogenetic tree illustrating the relatedness between the 62 Tunisian M. hominis clinical strains based on pathotype association. Strains in red are associated with gynecological infections pathotype and strains in blue are associated with infertility pathotype.

Article Snippet: The genome size of M. hominis reference strain PG21 (ATCC 23114) was estimated to be around 665 kb (Calcutt and Foecking, ), thus exceeding Mycoplasma genitalium genome (580 kb), the smallest genome of any organism that can be grown in pure culture (Fookes et al., ), by only 85 kb.

Techniques:

Co-infection numbers of several Mycoplasma spp. UU = Ureaplasma urealyticum ; UP = Ureaplasma parvum ; MH = Mycoplasma hominis ; MG = Mycoplasma genitalium ; MF = Mycoplasma fermentans .

Journal: Pathogens

Article Title: Molecular Exploration of Mycoplasma fermentans and Mycoplasma genitalium in Mexican Women with Cervicitis

doi: 10.3390/pathogens13111004

Figure Lengend Snippet: Co-infection numbers of several Mycoplasma spp. UU = Ureaplasma urealyticum ; UP = Ureaplasma parvum ; MH = Mycoplasma hominis ; MG = Mycoplasma genitalium ; MF = Mycoplasma fermentans .

Article Snippet: The reference Mycoplasma strains U. parvum ATCC 27815, U. urealyticum ATCC 27618, M. genitalium ATCC 33350, M. hominis ATCC 15488, and M. fermentans ATCC 19989 were used as positive controls.

Techniques: Infection